Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_1945KEGG: pab:PAB0539 hypothetical protein. (374 aa)    
Predicted Functional Partners:
Pisl_0509
PFAM: protein of unknown function DUF814; KEGG: pai:PAE3259 hypothetical protein.
 
    0.810
Pisl_1946
Hypothetical protein.
       0.709
Pisl_1947
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: afu:AF0668 hypothetical protein.
       0.508
Pisl_0934
SMART: helicase c2; KEGG: pai:PAE3526 hypothetical protein.
 
     0.458
Pisl_1661
KEGG: pai:PAE1636 hypothetical protein.
  
     0.435
Pisl_1113
KEGG: pai:PAE0831 hypothetical protein.
  
     0.420
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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