Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_1960Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE0328 thiamine transport ATP-binding protein; TC 3.A.1.1.-. (306 aa)    
Predicted Functional Partners:
Pisl_1958
TIGRFAM: ABC transporter, periplasmic binding protein, thiB subfamily; PFAM: extracellular solute-binding protein, family 1; KEGG: pai:PAE0331 thiamine-binding periplasmic protein.
 
  
  0.834
Pisl_1959
KEGG: pai:PAE0329 putative thiamine transport system permease protein.
  
 
 0.833
Pisl_0058
KEGG: pai:PAE3570 sulfate ABC transporter, permease protein, putative.
  
   0.770
Pisl_1961
KEGG: pai:PAE2590 hypothetical protein.
       0.522
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
     0.454
rpl2
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
     0.450
rpl14
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
     0.434
Pisl_0076
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pai:PAE0062 molybdenum transport system permease protein, putative.
 
  
 0.417
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.