Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_1970PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE0315 ABC-2 type transport system ATP-binding protein. (288 aa)    
Predicted Functional Partners:
Pisl_1969
PFAM: ABC-2 type transporter; KEGG: pai:PAE0316 ABC-2 type transport system, membrane protein.
  
  
 0.951
Pisl_2013
PFAM: ABC-2 type transporter; KEGG: pai:PAE0270 membrane protein.
 
  
 0.766
Pisl_1971
ATP-NAD/AcoX kinase; PFAM: regulatory protein, ArsR; ATP-NAD/AcoX kinase; KEGG: pai:PAE3116 hypothetical protein.
  
   0.695
Pisl_1972
PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: pai:PAE2330 sugar transporter, conjectural.
   
 
 0.516
Pisl_0902
PFAM: ABC-2 type transporter; KEGG: pai:PAE3065 ABC-2 type transport system, membrane protein.
  
  
 0.479
Pisl_0038
PFAM: transcriptional regulator PadR family protein; KEGG: pai:PAE0013 hypothetical protein.
 
  
 0.455
Pisl_1303
PFAM: transcriptional regulator PadR family protein; KEGG: pai:PAE1218 hypothetical protein.
 
  
 0.453
rpl2
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
   0.427
rpl14
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
 
    0.404
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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