Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Pisl_1975PFAM: TENA/THI-4 domain protein; KEGG: pai:PAE0171 hypothetical protein. (196 aa)    
Predicted Functional Partners:
Pisl_1974
Transcriptional activator, TenA family; PFAM: TENA/THI-4 domain protein; KEGG: pai:PAE0170 conserved protein (tenA homolog).
       0.786
Pisl_1976
PFAM: Protein of unknown function DUF1626; KEGG: sto:ST1761 hypothetical protein.
 
     0.758
Pisl_1973
PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: pai:PAE0176 metabolite transport protein.
       0.559
Pisl_0896
TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pai:PAE2261 cation efflux system protein, conjectural.
  
     0.516
Pisl_1431
PFAM: MscS Mechanosensitive ion channel; KEGG: pai:PAE1270 hypothetical protein.
  
     0.502
Pisl_0968
Glycogen synthase (ADP-glucose/UDP-glucose); PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: pai:PAE3429 glycogen synthase (starch (bacterial glycogen) synthase), putative.
  
     0.499
Pisl_1907
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase, IS605 OrfB; KEGG: pab:PAB2077 hypothetical protein.
  
     0.498
Pisl_1440
PFAM: protein of unknown function DUF6, transmembrane; KEGG: pai:PAE1372 hypothetical protein.
  
     0.497
Pisl_1736
PFAM: Conserved TM helix repeat-containing protein; KEGG: pai:PAE1788 conserved within P.aerophilum.
  
     0.486
Pisl_1067
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase, IS605 OrfB; KEGG: sso:SSO1916 second ORF in transposon ISC1913.
  
     0.482
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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