Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pisl_1992KEGG: pai:PAE2664 formate dehydrogenase delta subunit. (226 aa)    
Predicted Functional Partners:
Pisl_0649
Molybdopterin synthase subunit MoaD / molybdopterin synthase subunit MoaE; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE; thiamineS protein; KEGG: pai:PAE0727 molybdenum cofactor biosynthesis protein D/E.
     
 0.858
Pisl_1994
Formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: pai:PAE2662 formate dehydrogenase alpha subunit.
 
  
 0.829
Pisl_1991
KEGG: pai:PAE2665 hypothetical protein.
       0.777
Pisl_1988
PFAM: molydopterin dinucleotide-binding region; KEGG: tdn:Tmden_0500 twin-arginine translocation pathway signal.
  
  
 0.753
Pisl_1997
KEGG: pai:PAE2659 formate dehydrogenase protein fdhE.
  
  
 0.734
Pisl_1986
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: rxy:Rxyl_1613 4Fe-4S ferredoxin, iron-sulfur binding protein.
     
 0.718
Pisl_1995
Formate dehydrogenase beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: pai:PAE2661 formate dehydrogenase beta subunit.
     
 0.684
Pisl_1987
KEGG: hdu:HD1111 formate dehydrogenase, gamma subunit.
       0.678
Pisl_1989
Hypothetical protein.
       0.651
Pisl_1990
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: gme:Gmet_2239 4Fe-4S ferredoxin, iron-sulfur binding protein.
       0.651
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
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