Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pisl_2004PFAM: protein of unknown function DUF343; KEGG: pai:PAE0284 hypothetical protein. (140 aa)    
Predicted Functional Partners:
Pisl_2005
PFAM: protein of unknown function DUF134; KEGG: tko:TK0562 hypothetical protein.
 
     0.809
Pisl_1565
PFAM: Protein of unknown function DUF1512; KEGG: pai:PAE1446 hypothetical protein.
  
     0.716
Pisl_2003
KEGG: pai:PAE0297 hypothetical protein.
 
     0.709
Pisl_0816
PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1).
 
     0.693
Pisl_2006
Hypothetical protein.
       0.658
Pisl_0347
KEGG: pai:PAE2941 hypothetical protein.
  
     0.633
Pisl_0820
KEGG: pai:PAE2169 ribosomal protein S26.
  
     0.611
Pisl_1653
KEGG: pai:PAE1625 putative serine/threonine protein kinase.
  
     0.599
Pisl_1061
Alpha-phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pai:PAE0764 phosphomannomutase (pmm); Belongs to the phosphohexose mutase family.
       0.567
Pisl_0715
KEGG: pai:PAE1488 hypothetical protein.
       0.566
Your Current Organism:
Pyrobaculum islandicum
NCBI taxonomy Id: 384616
Other names: P. islandicum DSM 4184, Pyrobaculum islandicum DSM 4184, Pyrobaculum islandicum str. DSM 4184, Pyrobaculum islandicum strain DSM 4184
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.