node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN0075 | thrB | PSEEN0075 | PSEEN0074 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Homoserine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudomonas-type ThrB family. | 0.803 |
PSEEN2747 | hom | PSEEN2747 | PSEEN4252 | Putative 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | 0.915 |
PSEEN2747 | metE | PSEEN2747 | PSEEN4639 | Putative 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.906 |
PSEEN2747 | metH | PSEEN2747 | PSEEN3382 | Putative 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.973 |
PSEEN2747 | metY | PSEEN2747 | PSEEN2118 | Putative 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | O-acetylhomoserine sulfhydrylase; Function of strongly homologous gene; enzyme. | 0.925 |
PSEEN2747 | sahH | PSEEN2747 | PSEEN5037 | Putative 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.956 |
PSEEN2747 | thrB | PSEEN2747 | PSEEN0074 | Putative 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Homoserine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudomonas-type ThrB family. | 0.803 |
PSEEN3862 | hom | PSEEN3862 | PSEEN4252 | Threonine synthase; Function of strongly homologous gene; enzyme. | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | 0.963 |
PSEEN3862 | metH | PSEEN3862 | PSEEN3382 | Threonine synthase; Function of strongly homologous gene; enzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.553 |
PSEEN3862 | thrB | PSEEN3862 | PSEEN0074 | Threonine synthase; Function of strongly homologous gene; enzyme. | Homoserine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudomonas-type ThrB family. | 0.916 |
PSEEN3862 | thrC | PSEEN3862 | PSEEN4251 | Threonine synthase; Function of strongly homologous gene; enzyme. | Threonine synthase; Function of strongly homologous gene; enzyme. | 0.900 |
hom | PSEEN2747 | PSEEN4252 | PSEEN2747 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | Putative 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.915 |
hom | PSEEN3862 | PSEEN4252 | PSEEN3862 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | Threonine synthase; Function of strongly homologous gene; enzyme. | 0.963 |
hom | ilvE | PSEEN4252 | PSEEN2090 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | Branched-chain amino acid aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.971 |
hom | metE | PSEEN4252 | PSEEN4639 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.915 |
hom | metH | PSEEN4252 | PSEEN3382 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.952 |
hom | metY | PSEEN4252 | PSEEN2118 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | O-acetylhomoserine sulfhydrylase; Function of strongly homologous gene; enzyme. | 0.930 |
hom | sahH | PSEEN4252 | PSEEN5037 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.821 |
hom | thrB | PSEEN4252 | PSEEN0074 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | Homoserine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudomonas-type ThrB family. | 0.924 |
hom | thrC | PSEEN4252 | PSEEN4251 | Homoserine dehydrogenase; Function of strongly homologous gene; enzyme. | Threonine synthase; Function of strongly homologous gene; enzyme. | 0.989 |