Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mtgAPeptidoglycan transglycosylase, biosynthetic; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (236 aa)    
Predicted Functional Partners:
pbpA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 0.973
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 0.971
ftsI
Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
 
 
 0.958
mrcA
Penicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
0.936
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
  
0.928
dacB
D-alanyl-D-alanine carboxypeptidase; Function of strongly homologous gene; enzyme.
  
  
 0.922
dacC
D-ala-D-ala-carboxypeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S11 family.
  
 
 0.919
pbpC
Transglycosylase of penicillin-binding protein 1c; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
0.914
PSEEN0305
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.754
rlpA-2
Putative lipoprotein, rare lipoprotein A family; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
 
 
 
 0.656
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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