Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mmsA-2Methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (508 aa)    
Predicted Functional Partners:
mmsB
3-hydroxyisobutyrate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the HIBADH-related family.
 
 
 0.991
PSEEN0681
Beta-alanine--pyruvate transaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.941
prpC
Methylcitrate synthase (citrate synthase 2); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
 0.926
PSEEN1919
Putative acetyl-CoA synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
   
 0.923
PSEEN2586
Putative aldehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.923
fadA
3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
   
 0.921
fadFx
acyl-CoA dehydrogenase protein FadFx; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.919
bkdB
2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.918
fadDx
acetyl-coA synthetase/AMP-(fatty) acid ligase FadDx; Function of strongly homologous gene; enzyme.
  
 0.915
acs-1
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.915
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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