Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cyoDCytochrome o ubiquinol oxidase, subunit IV; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (110 aa)    
Predicted Functional Partners:
cyoA
Cytochrome o ubiquinol oxidase subunit II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
cyoB
Cytochrome o ubiquinol oxidase subunit I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the heme-copper respiratory oxidase family.
 
 0.999
cyoC
Cytochrome o ubiquinol oxidase subunit III; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
cyoE
Protoheme IX farnesyltransferase (heme O biosynthesis); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
  
 0.988
coxA
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
  
 0.979
PSEEN0059
Putative cytochrome c oxidase, subunit III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.979
coxB
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 0.923
cyoE1
Putative protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
  
  
 0.860
sdhC
Succinate dehydrogenase, cytochrome b556 subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.696
sdhB
Succinate dehydrogenase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.691
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.