STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSEEN1634Hypothetical protein; No homology to any previously reported sequences. (404 aa)    
Predicted Functional Partners:
birA
Putative biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.760
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
  
  
 0.519
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.499
hisE
phosphoribosyl-ATP pyrophosphatase; Function of strongly homologous gene; enzyme.
   
  
 0.486
polA
DNA polymerase I, 3'--> 5' polymerase, 5'--> 3' and 3'--> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.476
PSEEN4283
Putative lipoprotein UxpA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; membrane component.
 
   
 0.419
tyrB
Aromatic-amino-acid aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.408
PSEEN1266
Putative glycoprotein endopeptidase metalloprotease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.406
PSEEN1629
Putative transcriptional regulator, TetR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
 
    0.402
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.