STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acnBAconitate hydratase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aconitase/IPM isomerase family. (874 aa)    
Predicted Functional Partners:
icd
Isocitrate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.984
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
 
 0.983
prpC
Methylcitrate synthase (citrate synthase 2); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
 
 0.980
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.964
idh
Isocitrate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the monomeric-type IDH family.
 
 
 0.948
sucA
2-oxoglutarate dehydrogenase, E1 component; Function of strongly homologous gene; enzyme.
   
  
 0.942
aceA
Isocitrate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.931
prpD
2-methyl citrate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.928
prpB
Methylisocitrate lyase PrpB; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 
 0.917
PSEEN1906
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
    
 0.914
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.