Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSEEN2014Putative 4-hydroxyphenylpyruvate dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (634 aa)    
Predicted Functional Partners:
aroE-2
Putative shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
 
 0.980
aroQ-2
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
  
 
 0.942
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 
 0.932
PSEEN3214
Putative shikimate 5-dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 
 0.932
aroQ-1
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
  
 
 0.924
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
 
 0.910
quiA
Quinate dehydrogenase (pyrroloquinoline-quinone); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.900
PSEEN2015
Putative transcriptional regulator, TetR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
 
     0.895
pmsC
Isochorismate synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.834
pobA
P-hydroxybenzoate hydroxylase (4-hydroxybenzoate 3-monooxygenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.813
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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