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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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[Homology]
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PSEEN2129Putative dioxygenase, beta subunit; Converts carnitine to trimethylamine and malic semialdehyde. (324 aa)    
Predicted Functional Partners:
PSEEN1935
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
 0.916
PSEEN2130
Putative dioxygenase, alpha subunit; Converts carnitine to trimethylamine and malic semialdehyde.
 
  
 0.907
nuoC
NADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.882
PSEEN5528
Putative polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.838
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.796
iscU
Iron-sulfur cluster assembly protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.749
PSEEN5531
Putative polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.733
putA
Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
 0.685
PSEEN5169
Putative iron-sulfur cluster-binding protein, Rieske family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
  
 0.671
PSEEN2149
Putative non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.650
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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