STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C2-hpahP-hydroxyphenylacetate hydroxylase C2:oxygenase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (389 aa)    
Predicted Functional Partners:
C1-hpah
P-hydroxyphenylacetate hydroxylase C1:reductase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.992
hpaD
3,4-dihydroxyphenylacetate 2,3-dioxygenase (Homoprotocatechuate 2,3-dioxygenase) (HPC dioxygenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
  0.973
fadB
Fatty oxidation complex alpha subunit [Includes: Enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.792
PSEEN5528
Putative polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
 0.743
nuoC
NADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 0.737
hpaH
2-oxo-hepta-3-ene-1,7-dioic acid hydratase (OHED hydratase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.708
hpaA
4-hydroxyphenylacetate catabolism regulatory protein hpaA; Function of strongly homologous gene; regulator.
  
  
 0.664
PSEEN2149
Putative non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 
 0.644
PSEEN4615
Putative oxidoreductase, short chain dehydrogenase/reductase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.629
PSEEN2748
Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
   
 0.625
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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