Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
paaHPutative 3-hydroxybutyryl-CoA dehydrogenase; Function of strongly homologous gene; enzyme. (282 aa)    
Predicted Functional Partners:
phaA
enoyl-CoA hydratase/isomerase PhaA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.998
fadB1x
enoyl-CoA hydratase, FadB1x; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.998
PSEEN3197
Putative Acetoacetyl-CoA thiolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 0.995
phbA
acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 0.983
fadAx
acetyl-CoA acetyltransferase with thiolase domain FadAx; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 0.980
PSEEN0664
Putative acetyl-CoA acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.967
PSEEN2543
Putative 3-ketoacyl-CoA thiolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.965
fadB
Fatty oxidation complex alpha subunit [Includes: Enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 
0.940
lpsJ
acetoacetyl-CoA transferase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.938
paaB
enoyl-CoA hydratase/isomerase PhaB; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.931
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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