STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bkdA22-oxoisovalerate dehydrogenase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (352 aa)    
Predicted Functional Partners:
bkdA1
2-oxoisovalerate dehydrogenase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.999
bkdB
2-oxoisovalerate dehydrogenase, lipoamide acyltransferase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
lpdV
2-oxoisovalerate dehydrogenase, lipoamide dehydrogenase component; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
lpd
2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.994
lpd3
Dihydrolipoamide dehydrogenase 3; Function of strongly homologous gene; enzyme.
 
 0.994
sucB
2-oxoglutarate dehydrogenase, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.986
aceF
Dihydrolipoamide S-acetyltransferase, E2 component of the pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.985
prs
Ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.960
PSEEN4606
Putative leucine dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
 
 
 0.956
gor
Glutathione oxidoreductase, nucleotide-binding; Maintains high levels of reduced glutathione.
 
 0.939
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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