Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PSEEN4366Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (174 aa)    
Predicted Functional Partners:
PSEEN3914
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.713
PSEEN4365
Putative transcriptional regulator with cyclic nucleotide-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
 
     0.711
PSEEN1901
Putative transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
      
 0.618
lon-2
DNA-binding ATP-dependent protease La-2; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.526
PSEEN3614
Putative hydrolase, alpha/beta fold family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
     0.438
PSEEN0294
Putative transcriptional regulator, TetR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
  
     0.411
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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