A0A368UID0 protein (Glycine max) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

A0A368UID0

Uncharacterized protein. (523 aa)

Predicted Functional Partners:

A0A0R0ECE8

0.901

I1L367_SOYBN

0.900

K7KCC2_SOYBN

0.826

CHI3

0.701

I1L2W3_SOYBN

0.691

K7KWK9_SOYBN

0.666

PRP2

0.624

A0A0R0IPR5

0.601

A0A0R0HQY2

0.590

A0A0R0L3G5

0.590

Your Current Organism:

Glycine max

NCBI taxonomy Id: 3847
Other names: G. max, Glycine max (L.) Merr., soybean, soybeans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0R0ECE8	A0A0R0HQY2	A0A0R0ECE8	A0A0R0HQY2	Uncharacterized protein.	Amino_oxidase domain-containing protein.	0.590
A0A0R0ECE8	A0A0R0IPR5	A0A0R0ECE8	A0A0R0IPR5	Uncharacterized protein.	Uncharacterized protein.	0.601
A0A0R0ECE8	A0A0R0L3G5	A0A0R0ECE8	A0A0R0L3G5	Uncharacterized protein.	Amino_oxidase domain-containing protein.	0.590
A0A0R0ECE8	A0A368UID0	A0A0R0ECE8	A0A368UID0	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A0R0ECE8	CHI3	A0A0R0ECE8	A7ISP6	Uncharacterized protein.	Chalcone--flavonone isomerase 3; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).	0.701
A0A0R0ECE8	I1L2W3_SOYBN	A0A0R0ECE8	I1L2W3	Uncharacterized protein.	Uncharacterized protein.	0.691
A0A0R0ECE8	I1L367_SOYBN	A0A0R0ECE8	I1L367	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A0R0ECE8	K7KCC2_SOYBN	A0A0R0ECE8	K7KCC2	Uncharacterized protein.	Uncharacterized protein.	0.826
A0A0R0ECE8	K7KWK9_SOYBN	A0A0R0ECE8	K7KWK9	Uncharacterized protein.	Uncharacterized protein.	0.666
A0A0R0ECE8	PRP2	A0A0R0ECE8	P13993	Uncharacterized protein.	Repetitive proline-rich cell wall protein 2; This is a developmentally regulated putative cell wall protein; Belongs to the plant proline-rich protein superfamily. ENOD12 family.	0.624
A0A0R0HQY2	A0A0R0ECE8	A0A0R0HQY2	A0A0R0ECE8	Amino_oxidase domain-containing protein.	Uncharacterized protein.	0.590
A0A0R0HQY2	A0A0R0L3G5	A0A0R0HQY2	A0A0R0L3G5	Amino_oxidase domain-containing protein.	Amino_oxidase domain-containing protein.	0.900
A0A0R0HQY2	A0A368UID0	A0A0R0HQY2	A0A368UID0	Amino_oxidase domain-containing protein.	Uncharacterized protein.	0.590
A0A0R0HQY2	CHI3	A0A0R0HQY2	A7ISP6	Amino_oxidase domain-containing protein.	Chalcone--flavonone isomerase 3; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).	0.701
A0A0R0HQY2	I1L367_SOYBN	A0A0R0HQY2	I1L367	Amino_oxidase domain-containing protein.	Uncharacterized protein.	0.590
A0A0R0HQY2	K7KCC2_SOYBN	A0A0R0HQY2	K7KCC2	Amino_oxidase domain-containing protein.	Uncharacterized protein.	0.510
A0A0R0IPR5	A0A0R0ECE8	A0A0R0IPR5	A0A0R0ECE8	Uncharacterized protein.	Uncharacterized protein.	0.601
A0A0R0IPR5	A0A368UID0	A0A0R0IPR5	A0A368UID0	Uncharacterized protein.	Uncharacterized protein.	0.601
A0A0R0IPR5	I1L2W3_SOYBN	A0A0R0IPR5	I1L2W3	Uncharacterized protein.	Uncharacterized protein.	0.995
A0A0R0IPR5	I1L367_SOYBN	A0A0R0IPR5	I1L367	Uncharacterized protein.	Uncharacterized protein.	0.601

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.853

expected number of edges:

11

PPI enrichment p-value:

0.000307

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000819

Sister chromatid segregation

10 of 19

2.5

9.23

1.09e-20

GO:0007062

Sister chromatid cohesion

7 of 11

2.58

6.74

3.44e-14

GO:0022402

Cell cycle process

11 of 83

1.9

5.74

1.42e-18

GO:0000070

Mitotic sister chromatid segregation

6 of 13

2.44

5.27

2.32e-11

GO:0000280

Nuclear division

7 of 33

2.1

4.74

1.33e-11

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003682

Chromatin binding

5 of 35

1.93

2.54

3.02e-06

GO:0005488

Binding

11 of 2634

0.4

0.29

0.0222

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044815

DNA packaging complex

8 of 28

2.23

5.99

3.09e-14

GO:0008278

Cohesin complex

5 of 5

2.78

5.24

1.25e-10

GO:0005694

Chromosome

10 of 133

1.65

3.78

4.99e-14

GO:0000796

Condensin complex

3 of 4

2.65

2.67

1.13e-05

GO:0043232

Intracellular non-membrane-bounded organelle

11 of 494

1.13

1.62

8.78e-11

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4007

Sister chromatid segregation

10 of 13

2.66

10.43

2.88e-22

CL:4010

Establishment of Sister Chromatid Cohesion

6 of 6

2.78

6.42

5.26e-13

CL:4023

Chromosome condensation

3 of 5

2.56

2.48

2.39e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-2468052

Establishment of Sister Chromatid Cohesion

7 of 8

2.72

7.25

7.27e-15

MAP-68884

Mitotic Telophase/Cytokinesis

6 of 6

2.78

6.3

9.20e-13

MAP-2470946

Cohesin Loading onto Chromatin

6 of 6

2.78

6.3

9.20e-13

MAP-68877

Mitotic Prometaphase

9 of 47

2.06

5.68

4.67e-15

MAP-2500257

Resolution of Sister Chromatid Cohesion

6 of 31

2.07

4.03

8.54e-10

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0008278

Cohesin complex

5 of 5

2.78

5.22

1.38e-10

GOCC:0000793

Condensed chromosome

7 of 24

2.24

5.21

4.89e-12

GOCC:0005694

Chromosome

9 of 137

1.6

3.21

9.44e-12

GOCC:0043232

Intracellular non-membrane-bounded organelle

11 of 384

1.24

1.98

9.44e-12

GOCC:0000796

Condensin complex

2 of 4

2.48

1.38

0.0029

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13304

AAA domain, putative AbiEii toxin, Type IV TA system

2 of 3

2.6

1.05

0.0124

PF04825

N terminus of Rad21 / Rec8 like protein

2 of 2

2.78

1.05

0.0124

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039781

Rad21/Rec8-like protein

2 of 2

2.78

0.89

0.0247

IPR006910

Rad21/Rec8-like protein, N-terminal

2 of 2

2.78

0.89

0.0247

IPR036277

SMCs flexible hinge superfamily

2 of 4

2.48

0.88

0.0247

IPR024704

Structural maintenance of chromosomes protein

2 of 4

2.48

0.88

0.0247

IPR010935

SMCs flexible hinge

2 of 4

2.48

0.88

0.0247

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00968

SMC proteins Flexible Hinge Domain

2 of 4

2.48

1.1

0.0095

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