STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q91_0175Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (415 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4' kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 0.998
Q91_1776
Heptosyl transferase I.
  
 0.990
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.986
Q91_0927
Lipid A biosynthesis lauroyl acyltransferase subfamily.
 
  
 0.966
Q91_1777
Lipopolysaccharide heptosyltransferase II.
 
  
 0.956
waaM
Lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase superfamily protein.
 
  
 0.946
waaP
Lipopolysaccharide kinase RfaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family.
    
 0.904
waaG
UDP-glucose:LPS alpha 1,3-glucosyltransferase WaaG.
    
 0.904
Q91_1641
Sugar isomerase, KpsF/GutQ.
 
   
 0.878
lpxB
Glycosyl transferase, family 19; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.865
Your Current Organism:
Cycloclasticus sp. P1
NCBI taxonomy Id: 385025
Other names: C. sp. P1
Server load: low (28%) [HD]