STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
hypA-2Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)    
Predicted Functional Partners:
Q91_0792
Hydrogenase accessory protein HypB.
 
 
 0.981
Q91_0783
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.926
Q91_0782
Hydrogenase formation factor (HypE).
 
  
 0.923
hypF
Hydrogenase maturation factor; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.889
Q91_0790
Ni,Fe-hydrogenase maturation factor.
 
  
 0.885
Q91_0789
NAD-reducing hydrogenase, beta subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.844
Q91_0784
Hydrogenase assembly chaperone HypC/HupF.
 
  
 0.828
Q91_0786
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit.
     
 0.803
Q91_0158
ATPase, nucleotide-binding protein Mrp; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.781
Q91_0787
NAD-reducing hydrogenase, gamma subunit.
     
 0.768
Your Current Organism:
Cycloclasticus sp. P1
NCBI taxonomy Id: 385025
Other names: C. sp. P1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.