STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q91_1092Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (865 aa)    
Predicted Functional Partners:
Q91_1423
Citrate synthase-like protein.
 
 
 0.966
Q91_0050
Citrate synthase I; Belongs to the citrate synthase family.
  
 
 0.963
Q91_1187
Citrate synthase I.
  
 
 0.961
Q91_1570
Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
  
 
 0.934
prpB
PEP phosphonomutase and related enzyme; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
     
 0.922
mdh
Malate dehydrogenase 1; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.913
prpF
AcnD-accessory protein PrpF.
    
 0.910
icl
Isocitrate lyase family protein.
     
 0.909
sucC
Succinyl-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.875
sucA
Oxoglutarate dehydrogenase, E1 component.
   
  
 0.873
Your Current Organism:
Cycloclasticus sp. P1
NCBI taxonomy Id: 385025
Other names: C. sp. P1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.