STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q91_1141ABC cobalamin/Fe3+-siderophore transporter, periplasmic substrate-binding subunit. (281 aa)    
Predicted Functional Partners:
Q91_1139
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component.
 
 0.999
hmuU
Hemin transport system permease protein, HmuU; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.996
icmF
Adenosyl-cobalamine enzyme; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
  
 0.594
Q91_1138
Outer membrane receptor for transport of vitamin B.
 
  
 0.585
Q91_1355
AMP-dependent synthetase and ligase.
  
  
 0.541
Q91_1142
Hypothetical protein.
       0.518
Q91_0141
Metal chelate ABC transporter, metal chelate-binding protein.
 
     0.497
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
     
 0.490
Q91_0823
Iron permease FTR1 family.
   
  
 0.489
Q91_1303
Iron permease FTR1/Cytochrome c domain protein.
   
  
 0.489
Your Current Organism:
Cycloclasticus sp. P1
NCBI taxonomy Id: 385025
Other names: C. sp. P1
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.