STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceBMalate synthase A. (527 aa)    
Predicted Functional Partners:
icl
Isocitrate lyase family protein.
 
 0.999
Q91_0522
Malate dehydrogenase, Phosphate acetyltransferase.
  
 
 0.987
acsA
Acetyl-coenzyme A synthetase 2; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.960
Q91_0050
Citrate synthase I; Belongs to the citrate synthase family.
   
 0.943
Q91_1187
Citrate synthase I.
   
 0.941
Q91_1423
Citrate synthase-like protein.
   
 0.941
mdh
Malate dehydrogenase 1; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 0.940
prpB
PEP phosphonomutase and related enzyme; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
   
 
 0.938
Q91_1428
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.938
Q91_1512
Aminotransferase class V.
  
 
 0.920
Your Current Organism:
Cycloclasticus sp. P1
NCBI taxonomy Id: 385025
Other names: C. sp. P1
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