| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Q91_1461 | dnaK | Q91_1461 | Q91_1459 | Hypothetical protein. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.438 |
| Q91_1461 | grpE | Q91_1461 | Q91_1460 | Hypothetical protein. | Hsp 24 DnaK nucleotide exchange factor, probable member of theDnaK/DnaJ/GrpE foldase complex; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrat [...] | 0.572 |
| Q91_1461 | nadK | Q91_1461 | Q91_1462 | Hypothetical protein. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.467 |
| Q91_1461 | recN | Q91_1461 | Q91_1463 | Hypothetical protein. | ATPase involved in DNA repair, RecN; May be involved in recombinational repair of damaged DNA. | 0.461 |
| dnaK | Q91_1461 | Q91_1459 | Q91_1461 | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Hypothetical protein. | 0.438 |
| dnaK | grpE | Q91_1459 | Q91_1460 | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Hsp 24 DnaK nucleotide exchange factor, probable member of theDnaK/DnaJ/GrpE foldase complex; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrat [...] | 0.999 |
| dnaK | nadK | Q91_1459 | Q91_1462 | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.457 |
| dnaK | recN | Q91_1459 | Q91_1463 | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | ATPase involved in DNA repair, RecN; May be involved in recombinational repair of damaged DNA. | 0.591 |
| grpE | Q91_1461 | Q91_1460 | Q91_1461 | Hsp 24 DnaK nucleotide exchange factor, probable member of theDnaK/DnaJ/GrpE foldase complex; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrat [...] | Hypothetical protein. | 0.572 |
| grpE | dnaK | Q91_1460 | Q91_1459 | Hsp 24 DnaK nucleotide exchange factor, probable member of theDnaK/DnaJ/GrpE foldase complex; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrat [...] | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| grpE | nadK | Q91_1460 | Q91_1462 | Hsp 24 DnaK nucleotide exchange factor, probable member of theDnaK/DnaJ/GrpE foldase complex; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrat [...] | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.560 |
| grpE | recN | Q91_1460 | Q91_1463 | Hsp 24 DnaK nucleotide exchange factor, probable member of theDnaK/DnaJ/GrpE foldase complex; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrat [...] | ATPase involved in DNA repair, RecN; May be involved in recombinational repair of damaged DNA. | 0.526 |
| nadK | Q91_1461 | Q91_1462 | Q91_1461 | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Hypothetical protein. | 0.467 |
| nadK | dnaK | Q91_1462 | Q91_1459 | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.457 |
| nadK | grpE | Q91_1462 | Q91_1460 | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Hsp 24 DnaK nucleotide exchange factor, probable member of theDnaK/DnaJ/GrpE foldase complex; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrat [...] | 0.560 |
| nadK | recN | Q91_1462 | Q91_1463 | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | ATPase involved in DNA repair, RecN; May be involved in recombinational repair of damaged DNA. | 0.959 |
| recN | Q91_1461 | Q91_1463 | Q91_1461 | ATPase involved in DNA repair, RecN; May be involved in recombinational repair of damaged DNA. | Hypothetical protein. | 0.461 |
| recN | dnaK | Q91_1463 | Q91_1459 | ATPase involved in DNA repair, RecN; May be involved in recombinational repair of damaged DNA. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.591 |
| recN | grpE | Q91_1463 | Q91_1460 | ATPase involved in DNA repair, RecN; May be involved in recombinational repair of damaged DNA. | Hsp 24 DnaK nucleotide exchange factor, probable member of theDnaK/DnaJ/GrpE foldase complex; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrat [...] | 0.526 |
| recN | nadK | Q91_1463 | Q91_1462 | ATPase involved in DNA repair, RecN; May be involved in recombinational repair of damaged DNA. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.959 |