Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mvkMevalonate kinase. (322 aa)    
Predicted Functional Partners:
lwe0013
Phosphomevalonate kinase.
 
  
 0.998
mvaA
Hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 0.998
mvaD
Mevalonate diphosphate decarboxylase.
 
  
 0.994
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.926
mvaS
hydroxymethylglutaryl-CoA synthase.
 
  
 0.922
pheT
phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.531
speG
Spermidine N1-acetyltransferase.
       0.482
lwe0008
Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
  
    0.474
lwe1725
Deoxynucleoside kinase family protein.
 
     0.456
qoxB
Cytochrome aa3 quinol oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family.
  
    0.405
Your Current Organism:
Listeria welshimeri
NCBI taxonomy Id: 386043
Other names: L. welshimeri serovar 6b str. SLCC5334, Listeria welshimeri serovar 6b str. SLCC5334, Listeria welshimeri serovar 6b strain SLCC5334
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