STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTHFD1LMonofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X1. (990 aa)    
Predicted Functional Partners:
GART
Trifunctional purine biosynthetic protein adenosine-3.
  
 0.999
ATIC
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase.
  
 0.990
MTHFD2
Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.
 
 
0.981
MTHFD2L
Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.
 
 
0.981
SHMT1
LOW QUALITY PROTEIN: serine hydroxymethyltransferase, cytosolic.
  
 0.978
SHMT2
Serine hydroxymethyltransferase, mitochondrial.
  
 0.978
FTCD
Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase.
    
 0.977
MTR
5-methyltetrahydrofolate--homocysteine methyltransferase.
  
 
 0.969
DHFR
Dihydrofolate reductase.
  
 
 0.968
AMT
Aminomethyltransferase, mitochondrial isoform X1.
  
 0.954
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.