Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMX3Protein disulfide-isomerase TMX3 isoform X1. (459 aa)    
Predicted Functional Partners:
TIMM44
Mitochondrial import inner membrane translocase subunit TIM44 isoform X1.
 
      0.822
TMX1
Thioredoxin-related transmembrane protein 1.
   
 
 0.793
RIC3
Protein RIC-3 isoform X1.
    
 0.762
CANX
Calnexin.
   
 0.693
TMX4
Thioredoxin-related transmembrane protein 4 isoform X1.
   
 
 0.650
UNC50
Protein unc-50 homolog isoform X1.
      
 0.628
SCCPDH
Saccharopine dehydrogenase-like oxidoreductase.
      
 0.627
CLGN
LOW QUALITY PROTEIN: calmegin.
   
 0.555
ENSPCIP00000038425
annotation not available
      
 0.554
AKR7L
Aflatoxin B1 aldehyde reductase member 4-like.
    
 
 0.553
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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