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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMX3Protein disulfide-isomerase TMX3 isoform X1. (459 aa)    
Predicted Functional Partners:
TIMM44
Mitochondrial import inner membrane translocase subunit TIM44 isoform X1.
 
    
 0.824
UNC50
Protein unc-50 homolog isoform X1.
      
 0.600
RIC3
Protein RIC-3 isoform X1.
    
 0.587
ERO1B
ERO1-like protein beta.
   
 0.565
EMC6
ER membrane protein complex subunit 6.
      
 0.562
SCCPDH
Saccharopine dehydrogenase-like oxidoreductase.
      
 0.553
PRDX5
Peroxiredoxin-5, mitochondrial.
   
 0.553
MSRA
Mitochondrial peptide methionine sulfoxide reductase.
   
 0.526
ENSPCIP00000047718
annotation not available
   
 0.526
GSR
Glutathione reductase, mitochondrial.
   
 0.516
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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