STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGFBR1TGF-beta receptor type-1. (509 aa)    
Predicted Functional Partners:
TGFB1
Transforming growth factor beta-1.
    
 0.998
TGFBR2
TGF-beta receptor type-2.
   
0.998
SMAD7
Mothers against decapentaplegic homolog 7.
   
 0.998
TGFB3
Transforming growth factor beta-3.
    
 0.996
SMURF2
E3 ubiquitin-protein ligase SMURF2 isoform X1.
    
 0.996
GDF11
LOW QUALITY PROTEIN: growth/differentiation factor 11.
    
 0.995
MSTN
Growth/differentiation factor 8 isoform X1.
    
 0.987
SMAD4
Mothers against decapentaplegic homolog 4.
   
 0.981
TGFB2
LOW QUALITY PROTEIN: transforming growth factor beta-2.
    
 0.977
SMURF1
E3 ubiquitin-protein ligase SMURF1 isoform X1.
    
 0.975
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.