Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RPS6KA2Ribosomal protein S6 kinase alpha-2 isoform X1. (762 aa)    
Predicted Functional Partners:
RPS6KA1
Ribosomal protein S6 kinase alpha-1 isoform X1.
   
  0.995
RPS6KA3
LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3.
   
  0.993
MAPK3
Mitogen-activated protein kinase 1/3.
   
0.990
MAPK7
Mitogen-activated protein kinase 7 isoform X1.
   
0.987
TSC2
LOW QUALITY PROTEIN: tuberin.
   
 0.956
TSC1
Tuberous sclerosis 1.
    
 0.949
ATF4
Cyclic AMP-dependent transcription factor ATF-4.
    
 0.923
TBC1D7
TBC1 domain family member 7 isoform X1.
     
 0.911
ESR1
LOW QUALITY PROTEIN: estrogen receptor.
   
 0.910
MAPK1
Mitogen-activated protein kinase 1.
   
 0.909
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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