Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIGLEC1Sialoadhesin isoform X1. (1729 aa)    
Predicted Functional Partners:
SPN
Leukosialin.
   
 0.951
TOLLIP
Toll-interacting protein isoform X1.
   
 
 0.652
MUC1
Mucin-1.
    
 0.621
SIGLEC15
Sialic acid binding Ig-like lectin 15.
    
0.616
ADK
Adenosine kinase isoform X1.
    
 
 0.570
ST8SIA2
Alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8B).
      
 0.562
CMAS
N-acylneuraminate/3-deoxy-D-glycero-D-galacto-nononate cytidylyltransferase.
      
 0.561
NEU1
Sialidase-1.
      
 0.525
RSAD2
Radical S-adenosyl methionine domain-containing protein 2.
   
  
 0.524
CD68
Macrosialin isoform X1.
   
 
 0.524
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.