Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HYIPutative hydroxypyruvate isomerase. (275 aa)    
Predicted Functional Partners:
GRHPR
Glyoxylate reductase/hydroxypyruvate reductase.
  
 
 0.921
AGXT
Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase.
    
  0.900
AGXT2
Alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase.
   
 
  0.813
DAO
D-amino-acid oxidase.
     
  0.800
AP4E1
AP-4 complex subunit epsilon-1 isoform X1.
      
 0.743
PSMA2
Proteasome subunit alpha type-2.
      
 0.719
NCAPH
Condensin complex subunit 2 isoform X1.
      
 0.693
ARID4B
AT-rich interactive domain-containing protein 4B isoform X1.
      
 0.689
CCDC117
Coiled-coil domain-containing protein 117 isoform X1.
      
 0.685
GGPS1
Geranylgeranyl pyrophosphate synthase isoform X1.
      
 0.680
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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