STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIF1ANLOW QUALITY PROTEIN: hypoxia-inducible factor 1-alpha inhibitor. (348 aa)    
Predicted Functional Partners:
HIF1A
Hypoxia-inducible factor 1 alpha.
    
 0.986
TNKS2
Tankyrase-2 isoform X1.
    
 
 0.912
EPAS1
Endothelial PAS domain-containing protein 1.
    
 0.902
HIF3A
Hypoxia-inducible factor 3-alpha isoform X1.
    
 0.892
NOTCH1
LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1.
    
 
 0.883
PPP1R13B
Protein phosphatase 1 regulatory subunit 13B.
    
   0.814
PPP1R13L
RelA-associated inhibitor isoform X1.
    
   0.814
TRPA1
Transient receptor potential cation channel subfamily A member 1.
    
   0.814
ENSPCIP00000052893
Interleukin-10 receptor subunit beta-like.
    
   0.688
TNKS
Tankyrase-1.
    
 
 0.677
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.