Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF6LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor 6. (1542 aa)    
Predicted Functional Partners:
RAPGEF2
Rap guanine nucleotide exchange factor 2 isoform X1.
  
0.976
RAP1B
Ras-related protein Rap-1B.
    
 0.943
RAP1A
Ras-related protein Rap-1A.
    
 0.943
F11R
Junctional adhesion molecule 1.
     
 0.913
MAGI3
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X1.
    
 0.909
MAGI1
Membrane associated guanylate kinase, WW and PDZ domain containing 1.
    
 0.902
MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X1.
    
  0.900
PTPN13
LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 13.
    
 0.869
MRAS
Ras-related protein M-Ras.
    
 0.659
GRHL1
LOW QUALITY PROTEIN: grainyhead-like protein 1 homolog.
      
 0.638
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.