Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPHK2Sphingosine kinase 2. (247 aa)    
Predicted Functional Partners:
SGPL1
Sphinganine-1-phosphate aldolase.
   
 0.974
ENSPCIP00000002728
annotation not available
    
 0.967
ASAH1
Acid ceramidase.
     
 0.951
SGPP1
Sphingosine-1-phosphate phosphatase 1.
  
 0.946
SGPP2
Sphingosine-1-phosphate phosphatase 2 isoform X1.
  
 0.946
KDSR
3-ketodihydrosphingosine reductase isoform X1.
     
 0.943
ACER3
Alkaline ceramidase 3 isoform X1.
    
 0.942
ACER2
Alkaline ceramidase 2.
    
 0.942
ACER1
Alkaline ceramidase 1.
    
 0.942
PRKCB
Protein kinase C beta type isoform X1.
     
 0.938
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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