Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEP57Centrosomal protein of 57 kDa isoform X1. (496 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK1.
     
 0.818
CEP63
Centrosomal protein of 63 kDa isoform X1.
   
 
 0.773
DEUP1
Deuterosome assembly protein 1 isoform X1.
   
 
 0.684
PLK4
LOW QUALITY PROTEIN: serine/threonine-protein kinase PLK4.
     
 0.675
CEP70
Centrosomal protein 70.
     
 0.657
CEP192
Centrosomal protein of 192 kDa isoform X1.
   
 
 0.651
ACP7
Acid phosphatase type 7.
      
 0.628
TMLHE
Trimethyllysine dioxygenase, mitochondrial.
      
 0.628
ENSPCIP00000035187
annotation not available
     
 0.616
CEP164
Centrosomal protein of 164 kDa isoform X1.
     
 0.581
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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