close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SESN3Sestrin-3 isoform X1. (484 aa)    
Predicted Functional Partners:
PRKAA2
5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1.
     
 0.946
PRKAB1
5'-AMP-activated protein kinase, regulatory beta subunit.
     
 0.944
SESN2
Sestrin 2.
  
  
0.943
PRKAA1
5'-AMP-activated protein kinase catalytic subunit alpha-1.
     
 0.942
PRKAB2
5'-AMP-activated protein kinase, regulatory beta subunit.
     
 0.941
PRKAG1
5'-AMP-activated protein kinase subunit gamma-1 isoform X1.
   
 
 0.938
PRKAG2
5'-AMP-activated protein kinase subunit gamma-2 isoform X1.
   
 
 0.938
SESN1
Sestrin-1 isoform X1.
  
  
0.923
DEPDC5
DEP domain-containing protein 5 isoform X1.
    
 0.776
WDR24
WD repeat-containing protein 24.
    
 0.756
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.