Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SESN3Sestrin-3 isoform X1. (484 aa)    
Predicted Functional Partners:
WDR24
WD repeat-containing protein 24.
    
 0.974
SESN2
Sestrin 2.
  
 
 
0.932
SESN1
Sestrin-1 isoform X1.
  
  
 
0.909
WDR59
WD repeat-containing protein 59 isoform X1.
    
 0.878
NPRL3
Nitrogen permease regulator 3-like protein isoform X1.
    
 0.869
PRKAA2
5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1.
     
 0.846
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
   
 
 0.843
DEPDC5
DEP domain-containing protein 5 isoform X1.
    
 0.840
PRKAB2
5'-AMP-activated protein kinase, regulatory beta subunit.
     
 0.839
SEH1L
Nucleoporin SEH1 isoform X1.
    
 0.825
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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