Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISG15Ubiquitin cross-reactive protein. (160 aa)    
Predicted Functional Partners:
DDX58
Probable ATP-dependent RNA helicase DDX58 isoform X1.
   
 0.999
IRF3
Interferon regulatory factor 3 isoform X1.
   
 0.997
UBE2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X1.
   
 0.995
IFIH1
Interferon-induced helicase C domain-containing protein 1.
   
 0.994
IRF9
Interferon regulatory factor 9.
   
 0.988
USP18
Ubl carboxyl-terminal hydrolase 18 isoform X1.
   
 0.982
EIF2AK2
Interferon-induced, double-stranded RNA-activated protein kinase.
   
 
 0.977
UBA7
LOW QUALITY PROTEIN: ubiquitin-like modifier-activating enzyme 7.
   
 0.976
UBA1
Ubiquitin-like modifier-activating enzyme 1.
   
 0.976
NEDD4
E3 ubiquitin-protein ligase NEDD4 isoform X1.
    
 0.971
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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