Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HTRA1HtrA serine peptidase 1. (486 aa)    
Predicted Functional Partners:
XIAP
E3 ubiquitin-protein ligase XIAP.
    
 
 0.648
SCP2
Non-specific lipid-transfer protein.
    
 0.643
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13.
   
 0.642
ECI2
Enoyl-CoA delta isomerase 2, mitochondrial.
    
 0.615
MAPT
Microtubule-associated protein tau isoform X1.
    
 
 0.609
BIRC6
Baculoviral IAP repeat-containing protein 6 isoform X1.
    
 0.607
PINK1
LOW QUALITY PROTEIN: serine/threonine-protein kinase PINK1, mitochondrial.
    
 
 0.593
GCM1
Chorion-specific transcription factor GCMa.
    
 
 0.590
PSMD1
LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 1.
    
 0.569
PSMD12
26S proteasome non-ATPase regulatory subunit 12 isoform X1.
    
 0.540
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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