STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS2Suppressor of cytokine signaling 2 isoform X1. (264 aa)    
Predicted Functional Partners:
CUL5
Cullin 5.
   
 0.976
JAK2
LOW QUALITY PROTEIN: tyrosine-protein kinase JAK2.
    
 0.957
SOCS3
Suppressor of cytokine signaling 3.
    
0.952
SOCS4
Suppressor of cytokine signaling 4.
     
0.940
INSR
Insulin receptor isoform X1.
    
 0.924
IRS1
Insulin receptor substrate 1.
    
 0.913
IRS2
Insulin receptor substrate 2 isoform X1.
    
 0.913
ENSPCIP00000000460
annotation not available
    
 0.831
ENSPCIP00000011368
annotation not available
    
 0.831
ELOC
Elongin-C.
    
 0.831
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.