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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AURKBAurora kinase B isoform X1. (351 aa)    
Predicted Functional Partners:
INCENP
Inner centromere protein isoform X1.
   
 0.990
CDCA8
Borealin.
   
 0.989
BIRC5
Baculoviral IAP repeat-containing protein 5 isoform X1.
   
 0.988
CDK1
Cyclin-dependent kinase 1.
  
0.965
CCNA2
Cyclin-A2.
   
 
 0.954
CENPA
LOW QUALITY PROTEIN: histone H3-like centromeric protein A.
   
 
 0.950
TPX2
Targeting protein for Xklp2 isoform X1.
   
 0.936
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.931
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1.
   
 0.927
PLK1
Serine/threonine-protein kinase PLK1.
   
0.924
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.