STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKN2CCyclin-dependent kinase 4 inhibitor C. (185 aa)    
Predicted Functional Partners:
CDK6
Cyclin-dependent kinase 6 isoform X1.
   
 0.999
CDK4
Cyclin-dependent kinase 4.
   
 0.998
CCND1
G1/S-specific cyclin-D1.
    
 0.968
CCND2
G1/S-specific cyclin-D2.
    
 0.960
CCND3
G1/S-specific cyclin-D3 isoform X1.
    
 0.960
TP53
Cellular tumor antigen p53.
    
 0.931
CDK2
Cyclin-dependent kinase 2 isoform X1.
   
 0.723
CDK1
Cyclin-dependent kinase 1.
   
 0.701
CDK3
Cyclin dependent kinase 3.
   
 0.692
CDKN1A
Cyclin-dependent kinase inhibitor 1 isoform X1.
    
 0.626
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.