Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF11Rho guanine nucleotide exchange factor 11. (1595 aa)    
Predicted Functional Partners:
GNA13
Guanine nucleotide-binding protein subunit alpha-13.
    
 0.995
GNA12
Guanine nucleotide-binding protein subunit alpha-12.
    
 0.987
RHOA
Ras homolog gene family, member A.
   
 0.980
ARHGEF1
Rho guanine nucleotide exchange factor 1.
     
0.942
ARHGEF12
Rho guanine nucleotide exchange factor 12 isoform X1.
    
0.938
AKAP13
A-kinase anchor protein 13 isoform X1.
   
0.933
CDC42
Cell division control protein 42 homolog isoform X1.
   
 0.882
PLXNB2
LOW QUALITY PROTEIN: plexin-B2.
    
 0.877
PLXNB3
LOW QUALITY PROTEIN: plexin-B3.
    
 0.871
PLXNB1
Plexin B1.
    
 0.871
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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