STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APLP2Amyloid-like protein 2 isoform X1. (764 aa)    
Predicted Functional Partners:
NCSTN
Nicastrin isoform X1.
    
 0.825
APBB1
Amyloid beta A4 precursor protein-binding family B member 1 isoform X1.
    
 0.795
PSEN2
Presenilin-2 isoform X1.
    
 
 0.780
PSEN1
Presenilin 1.
    
 
 0.766
IDE
Insulin-degrading enzyme isoform X1.
    
 
 0.732
ENSPCIP00000019661
annotation not available
    
 0.717
PRNP
Major prion protein.
   
 0.712
TNFRSF21
LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 21.
    
 
 0.709
GSN
LOW QUALITY PROTEIN: gelsolin.
   
 0.707
GHSR
Growth hormone secretagogue receptor type 1.
    
 0.700
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.