Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HOGA1LOW QUALITY PROTEIN: 4-hydroxy-2-oxoglutarate aldolase, mitochondrial. (328 aa)    
Predicted Functional Partners:
GRHPR
Glyoxylate reductase/hydroxypyruvate reductase.
  
 0.979
GOT2
LOW QUALITY PROTEIN: aspartate aminotransferase, mitochondrial.
   
 0.966
HAO1
Hydroxyacid oxidase 1 isoform X1.
   
 
 0.947
AGXT
Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase.
   
 
 0.944
HAO2
Hydroxyacid oxidase 2 isoform X1.
   
 
 0.918
AGXT2
Alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase.
   
 0.910
GOT1
Aspartate aminotransferase, cytoplasmic.
   
 0.908
GOT1L1
Putative aspartate aminotransferase, cytoplasmic 2 isoform X1.
   
  0.907
DAO
D-amino-acid oxidase.
   
 
 0.831
PRODH2
Probable proline dehydrogenase 2 isoform X1.
   
  
 0.644
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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