Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPLN-acetylneuraminate lyase isoform X1. (348 aa)    
Predicted Functional Partners:
CMAS
N-acylneuraminate/3-deoxy-D-glycero-D-galacto-nononate cytidylyltransferase.
   
 0.937
GNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1.
    
 0.930
NANP
N-acylneuraminate-9-phosphatase isoform X1.
   
 
 0.930
NANS
Sialic acid synthase.
   
 0.924
ENSPCIP00000007620
Cytidine monophosphate-N-acetylneuraminic acid hydroxylase isoform X1.
    
 0.917
AKR7L
Aflatoxin B1 aldehyde reductase member 4-like.
  
 0.548
GRHPR
Glyoxylate reductase/hydroxypyruvate reductase.
  
 0.480
GCLC
Glutamate--cysteine ligase catalytic subunit isoform X1.
   
 0.478
PYCR3
Pyrroline-5-carboxylate reductase 3.
      
 0.469
AGXT
Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase.
   
  
 0.463
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.