Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RABGEF1Rab5 GDP/GTP exchange factor isoform X1. (491 aa)    
Predicted Functional Partners:
RABEP1
Rab GTPase-binding effector protein 1 isoform X1.
   
 0.991
RAB5A
Ras-related protein Rab-5A.
   
 0.987
RAB5C
Ras-related protein Rab-5C.
   
 0.987
RAB5B
Ras-related protein Rab-5B.
   
 0.987
RABEP2
Rab GTPase-binding effector protein 2 isoform X1.
   
 0.968
GGA1
ADP-ribosylation factor-binding protein GGA1.
   
 0.923
RAB24
Ras-related protein Rab-24 isoform X1.
   
 0.900
RAB21
Ras-related protein Rab-21.
    
 0.899
RAB17
Ras-related protein Rab-17.
   
 0.885
ENSPCIP00000054824
annotation not available
   
 0.885
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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