Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1. (980 aa)    
Predicted Functional Partners:
HSPA5
Endoplasmic reticulum chaperone BiP.
    
 0.999
XBP1
LOW QUALITY PROTEIN: X-box-binding protein 1.
    
 0.987
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
    
0.986
TRAF2
TNF receptor-associated factor 2 isoform X1.
   
 0.979
PSEN1
Presenilin 1.
    
 0.925
PSEN2
Presenilin-2 isoform X1.
    
 0.914
SYVN1
Synoviolin 1.
    
 
 0.864
TRAF1
TNF receptor-associated factor 1 isoform X1.
   
 0.799
ATF6
Cyclic AMP-dependent transcription factor ATF-6 alpha isoform X1.
    
 0.782
ANKRD45
Ankyrin repeat domain-containing protein 45 isoform X1.
    
 0.702
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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