Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNF143Zinc finger protein 143 isoform X1. (638 aa)    
Predicted Functional Partners:
THAP11
THAP domain-containing protein 11.
     
 0.926
HCFC1
Host cell factor C1.
    
 0.913
ZNF76
LOW QUALITY PROTEIN: zinc finger protein 76.
  
  
 
0.901
SP1
Transcription factor Sp1.
    
  0.726
POU2F1
POU domain, class 2, transcription factor 1 isoform X1.
    
 0.661
EZH2
Histone-lysine N-methyltransferase EZH2 isoform X1.
   
 0.610
EZH1
[histone H3]-lysine27 N-trimethyltransferase EZH1.
   
 0.608
RNF2
E3 ubiquitin-protein ligase RNF1/2.
   
 0.597
SOX10
Transcription factor SOX7/8/10/18 (SOX group E/F).
    
 0.594
SUZ12
Polycomb protein SUZ12.
    
 0.593
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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