KIT protein (Phascolarctos cinereus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

KIT

Mast/stem cell growth factor receptor Kit isoform X1. (973 aa)

Predicted Functional Partners:

KITLG

0.990

GRB2

0.989

PIK3R1

0.988

CSF1

0.977

PIK3CA

0.971

PTPN11

0.968

PIK3R2

0.964

PIK3R3

0.964

ENSPCIP00000013537

0.962

STAT3

0.961

Your Current Organism:

Phascolarctos cinereus

NCBI taxonomy Id: 38626
Other names: P. cinereus, koala

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSF1	KIT	ENSPCIP00000004426	ENSPCIP00000007854	Macrophage colony-stimulating factor 1 isoform X1.	Mast/stem cell growth factor receptor Kit isoform X1.	0.977
CSF1	STAT3	ENSPCIP00000004426	ENSPCIP00000034506	Macrophage colony-stimulating factor 1 isoform X1.	Signal transducer and activator of transcription 3 isoform X1.	0.413
ENSPCIP00000013537	GRB2	ENSPCIP00000013537	ENSPCIP00000049493	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Growth factor receptor-binding protein 2.	0.997
ENSPCIP00000013537	KIT	ENSPCIP00000013537	ENSPCIP00000007854	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Mast/stem cell growth factor receptor Kit isoform X1.	0.962
ENSPCIP00000013537	KITLG	ENSPCIP00000013537	ENSPCIP00000047122	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	KIT ligand.	0.465
ENSPCIP00000013537	PIK3CA	ENSPCIP00000013537	ENSPCIP00000008142	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.965
ENSPCIP00000013537	PIK3R1	ENSPCIP00000013537	ENSPCIP00000010629	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.978
ENSPCIP00000013537	PIK3R2	ENSPCIP00000013537	ENSPCIP00000037290	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.958
ENSPCIP00000013537	PIK3R3	ENSPCIP00000013537	ENSPCIP00000037379	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.958
ENSPCIP00000013537	PTPN11	ENSPCIP00000013537	ENSPCIP00000025080	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Tyrosine-protein phosphatase non-receptor type 11 isoform X1.	0.901
ENSPCIP00000013537	STAT3	ENSPCIP00000013537	ENSPCIP00000034506	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	Signal transducer and activator of transcription 3 isoform X1.	0.699
GRB2	ENSPCIP00000013537	ENSPCIP00000049493	ENSPCIP00000013537	Growth factor receptor-binding protein 2.	Tyrosine-protein phosphatase non-receptor type 11-like isoform X1.	0.997
GRB2	KIT	ENSPCIP00000049493	ENSPCIP00000007854	Growth factor receptor-binding protein 2.	Mast/stem cell growth factor receptor Kit isoform X1.	0.989
GRB2	KITLG	ENSPCIP00000049493	ENSPCIP00000047122	Growth factor receptor-binding protein 2.	KIT ligand.	0.475
GRB2	PIK3CA	ENSPCIP00000049493	ENSPCIP00000008142	Growth factor receptor-binding protein 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.	0.707
GRB2	PIK3R1	ENSPCIP00000049493	ENSPCIP00000010629	Growth factor receptor-binding protein 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.976
GRB2	PIK3R2	ENSPCIP00000049493	ENSPCIP00000037290	Growth factor receptor-binding protein 2.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.818
GRB2	PIK3R3	ENSPCIP00000049493	ENSPCIP00000037379	Growth factor receptor-binding protein 2.	Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.	0.818
GRB2	PTPN11	ENSPCIP00000049493	ENSPCIP00000025080	Growth factor receptor-binding protein 2.	Tyrosine-protein phosphatase non-receptor type 11 isoform X1.	0.997
GRB2	STAT3	ENSPCIP00000049493	ENSPCIP00000034506	Growth factor receptor-binding protein 2.	Signal transducer and activator of transcription 3 isoform X1.	0.661